Hydrochloric Acid → HCID 21548938, compound

HRID 1605057Notes

Reaction equation

HRID 1605057 reaction equation
O=[C:2]1[C:15]2[CH:14]=[C:13]([CH:16]([CH3:19])[CH2:17][OH:18])[CH:12]=[CH:11][C:10]=2[O:9][C:8]2[C:3]1=[CH:4][CH:5]=[CH:6][CH:7]=2.O.Cl>[Zn].C1(C)C=CC=CC=1>[CH:14]1[C:15]2[CH2:2][C:3]3[C:8](=[CH:7][CH:6]=[CH:5][CH:4]=3)[O:9][C:10]=2[CH:11]=[CH:12][C:13]=1[CH:16]([CH3:19])[CH2:17][OH:18]

Participants

6

Reactant 3

HCID 313Hydrochloric Acid2×HCID 962WaterHCID 21548981HCID 21548981, compound

Product 1

HCID 21548938HCID 21548938, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 1140TolueneSolvent

Procedure

A mixture of 10 g. of 2-(9-oxo-2-xanthenyl)-propanol, 12 g. of amalgamized zinc, 15 ml. of water, 40 ml. of concentrated hydrochloric acid, and 20 ml. of toluene is refluxed for 48 hours. At 8 hour intervals, another 10 ml. of concentrated hydrochloric acid is added. After filtration over active carbon and removal of the solvent mixture by evaporation, 2-(2-xanthenyl)-propanol is obtained, m.p. 86°-89°.

Workup

  1. additionA mixture of 10 g
  2. filtrationAfter filtration
  3. customover active carbon and removal of the solvent mixture
  4. customby evaporation

Sources & evidence

ORD record
ord-5264427ccc0540bc820d5f6f1154f647
Source dataset
uspto-grants-1976_04
Patent number
US03948949

Reaction notes

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