Benzyl Chloride → HCID 21548681, compound

HRID 1605094Notes

Reaction equation

HRID 1605094 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:13](=[CH:14][CH:15]=1)[NH:12][C:11]1[CH2:10][CH2:9][CH2:8][CH:7]([C:16]([OH:18])=[O:17])[C:6]2=1.[CH2:19](Cl)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.C(=O)([O-])[O-].[Na+].[Na+]>CN(C)C=O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:13](=[CH:14][CH:15]=1)[NH:12][C:11]1[CH2:10][CH2:9][CH2:8][CH:7]([C:16]([O:18][CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[O:17])[C:6]2=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 10340Sodium CarbonateHCID 21548491HCID 21548491, compound

Product 1

HCID 21548681HCID 21548681, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following a procedure similar to that of Example 34C but using 37.2 g. of 6-methoxy-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 19.5 g. of benzyl chloride and 16.8 g. of sodium carbonate in 300 ml. of dry dimethylformamide there was obtained 40.3 g. of the title compound; m.p. 81°-83°C. (ethyl alcoholpentane).

Sources & evidence

ORD record
ord-24668370acd549edb3a817901586e8ed
Source dataset
uspto-grants-1976_04
Patent number
US03948939

Reaction notes

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