Methylamine → HCID 21549476, compound

Participants

Reaction Steps

A suspension of 0.35 g. of platinum oxide in 30 ml. of absolute ethanol is hydrogenated at 50 p.s.i. for one hour. To this is added a mixture of 13.8 g. of 1-(3-oxobutyl)-imidazole, 6.2 g. of methylamine and 60 ml. of ethanol. The mixture is shaken under ca. 50 p.s.i. of hydrogen until one equivalent is absorbed. Filtration of the catalyst and removal of solvent in vacuo gives 1-(3-methylaminobutyl)-imidazole.

Provenance & Evidence