Methylamine → HCID 21549501, compound

HRID 1605152Notes

Reaction equation

HRID 1605152 reaction equation
O=[C:2]([CH3:10])[CH2:3][N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[CH3:9].[CH3:11][NH2:12]>[Pt]=O.C(O)C>[CH3:11][NH:12][CH:2]([CH3:10])[CH2:3][N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[CH3:9]

Participants

5

Reactant 2

HCID 6329MethylamineHCID 21549496HCID 21549496, compound

Product 1

HCID 21549501HCID 21549501, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent2×

Procedure

A suspension of 0.20 g. of platinum oxide in 20 ml. of absolute ethanol is hydrogenated at 50 p.s.i. for one hour. To this is added a mixture of 7.0 g. of 1-(2-oxopropyl)-2-methyl-2-imidazoline, 3.1 g. of methylamine and 30 ml. of ethanol. The mixture is shaken under ca. 50 p.s.i. of hydrogen until one equivalent is absorbed. Filtration of the catalyst and removal of solvent in vacuo gives 1-(2-methylaminopropyl)-2-methyl-2-imidazoline.

Workup

  1. additionA suspension of 0.20 g
  2. additionTo this is added
  3. additiona mixture of 7.0 g
  4. customof hydrogen until one equivalent is absorbed
  5. filtrationFiltration of the catalyst and removal of solvent in vacuo

Sources & evidence

ORD record
ord-a7a0f1d4e68544a1abac084ee594f253
Source dataset
uspto-grants-1976_04
Patent number
US03949076

Reaction notes

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