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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1605172Generated: November 1, 2026

Hydrochloric Acid → 4-Aminobenzophenone

https://huagongshe.com/reaction/1605172

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantN-(4-benzoylphenyl)acetamideHCID 228532—
Product4-AminobenzophenoneHCID 14346—

Reaction Steps

p-Benzoylacetanilide (2.8 g.) and 100 ml. of 1N hydrochloric acid are refluxed for six hours. After cooling, the solution is made alkaline by the addition of 2N sodium hydroxide solution and extracted with ether to give 4-aminobenzophenone, which is recrystallized from methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03949084
Source datasetuspto-grants-1976_04
ORD IDord-a72f84d7ffd64c59ba1cab791580eabc
Source noteuspto-grants-1976_04