反应详情

A stirred mixture of 13.93 g. (0.07 mole) of (4-chloro-6-methyl-2-pyrimidinylthio)acetonitrile, 10.5 g. (0.07 mole) of piperonylamine and 7.42 g. (0.07 mole) of sodium carbonate in 100 ml of ethanol was heated under reflux for five hours. The mixture was filtered and the filtrate was cooled in ice. The precipitate thus formed was collected and recrystallized from absolute ethanol to give 15.7 g. of product, m.p. 115°-118°.

1. additionA stirred mixture of 13.93 g
2. temperatureunder reflux for five hours
3. filtrationThe mixture was filtered
4. temperaturethe filtrate was cooled in ice
5. customThe precipitate thus formed
6. customwas collected
7. customrecrystallized from absolute ethanol
8. customto give 15.7 g