HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → (4-Methyl-6-piperonylamino-2-pyrimidinylthio)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | Acetonitrile, [(4-chloro-6-methyl-2-pyrimidinyl)thio]- | HCID 12228966 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (4-Methyl-6-piperonylamino-2-pyrimidinylthio)acetonitrile | HCID 12228971 | — |
Reaction Steps
A stirred mixture of 13.93 g. (0.07 mole) of (4-chloro-6-methyl-2-pyrimidinylthio)acetonitrile, 10.5 g. (0.07 mole) of piperonylamine and 7.42 g. (0.07 mole) of sodium carbonate in 100 ml of ethanol was heated under reflux for five hours. The mixture was filtered and the filtrate was cooled in ice. The precipitate thus formed was collected and recrystallized from absolute ethanol to give 15.7 g. of product, m.p. 115°-118°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03950339 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-94ecfe17e6e54d1bb0dedb5b1ad8e602 |
| Source note | uspto-grants-1976_04 |