HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 12800574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Cephalothin Sodium | HCID 23675321 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12800574 | HCID 12800574 | 99.7% |
Reaction Steps
21.6 g of sodium cephalothin was dissolved in 500 ml of water and layered with 500 ml ethyl acetate. The mixture was acidified to pH4 by addition of 6N HCl and the product was extracted into the ethyl acetate phase, which was dried (MgSO4) and evaporated in vacuo to yield 20.4 g of 3-acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid, mp 152°-154°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03950329 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-7e56421309f445689b11c7a2e536f2b7 |
| Source note | uspto-grants-1976_04 |