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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1605483Generated: October 25, 2026

Ethylenediamine → N-(2-Dimethylaminoethyl)-N'-[2-(2-benzimidazolylmethylamino)-ethyl]thiourea

https://huagongshe.com/reaction/1605483

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant2-ChloromethylbenzimidazoleHCID 78571—
Reactant(2-Isothiocyanatoethyl)dimethylamineHCID 3853726—
ProductN-(2-Dimethylaminoethyl)-N'-[2-(2-benzimidazolylmethylamino)-ethyl]thioureaHCID 54373380—

Reaction Steps

N-(2-Benzimidiazolylmethyl)ethylenediamine, prepared by reacting ethylenediamine with 2-chloromethyl-benzimidazole by the procedure of Example 40, is reacted with 2-dimethylaminoethyl isothiocyanate by the procedure of Example 40 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03950353
Source datasetuspto-grants-1976_04
ORD IDord-26dc98511a5f49779474b95a0cb264db
Source noteuspto-grants-1976_04