HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (2E)-3-ethoxy-2-butenoate → (E)-4-(3-chloro-4-cycloheptyl-phenyl)-3-pentene-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (2E)-3-ethoxy-2-butenoate | HCID 5354173 | — |
| Reactant | 3'-Chloro-4'-cycloheptyl-acetophenone | HCID 21484428 | — |
| Product | (E)-4-(3-chloro-4-cycloheptyl-phenyl)-3-pentene-2-one | HCID 68135195 | 51% |
Reaction Steps
(E)-4-(3-chloro-4-cycloheptyl-phenyl)-3-pentene-2-one was prepared analogous to Example 52 from 3'-chloro-4'-cycloheptyl-acetophenone (b.p. 136°-139°C at 0.1 mm Hg; nD23 = 1.5572) and ethyl (E)-3-ethoxy-crotonate with a yield of 51% of theory. B.p. 160°-165°C at 0.1 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03950427 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-7af19697a43b45ee9c7cc221b4f49e0d |
| Source note | uspto-grants-1976_04 |