HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → Diethyl (3-methoxycarbonyl-4-methylthienyl)aminomethylenemalonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | Methyl 2-amino-4-methylthiophene-3-carboxylate | HCID 2759773 | — |
| Product | Diethyl (3-methoxycarbonyl-4-methylthienyl)aminomethylenemalonate | HCID 13217727 | — |
Reaction Steps
Reaction of methyl 2-amino-4-methylthiophene-3-carboxylate with diethyl ethoxymethylenemalonate in a manner similar to that used in Reference Example 10 yields diethyl (3-methoxycarbonyl-4-methylthienyl)aminomethylenemalonate as crystals melting at 105.5°-106°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03951989 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-e9e3152360a14acd819c8104e586717c |
| Source note | uspto-grants-1976_04 |