Benzoyl Peroxide → HCID 12562677, compound

Participants

Reaction Steps

N-Bromosuccinimide (26 g.) was added to a cold solution of 5-methyl-3-(4-chlorophenyl)-1,2-benzisoxazole (35 g.) in carbon tetrachloride (250 ml.). Benzoyl peroxide (500 mg.) was added and the mixture was heated under reflux for 3 hours in the presence of U.V. light. The solid residue was filtered off, and the filtrate was evaporated to give 5-bromomethyl-3-(4-chlorophenyl)-1,2-benzisoxazole (m.p. 142°C.).

Provenance & Evidence