Sodium Carbonate → HCID 12562671, compound

Participants

Reaction Steps

4'-Chloro-2-hydroxy-4-methylbenzophenone-oxime (0.2g) and anhydrous sodium carbonate (0.2g) were heated together under reflux in triglyome (5ml) for 30 minutes. On cooling, the mixture was poured into water (50ml.) and filtered. On standing a solid separated from the filtrate and was filtered, washed, dried and examined by NMR. The NMR spectrum was consistent with the preparation of the title compound (~30%). T.L.C. also confirmed the presence of the benzisoxazole.

Provenance & Evidence