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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1606117Generated: November 2, 2026

Water → HCID 21546014, compound

https://huagongshe.com/reaction/1606117

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantHCID 12212451HCID 12212451—
ProductHCID 21546014HCID 21546014—

Reaction Steps

The oxetane ring in these macrocycles can be opened, by addition of water as well as of alcohols. For example, acid-catalysed hydrolysis of 2,6,12,15,21-pentaoxa-9,18-diazaspiro[3.18]docosane yields 12,12-bis(hydroxymethyl)-1,4,10,14-tetraoxa-7,17-diazacyclononadecane. ##EQU16##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03952015
Source datasetuspto-grants-1976_04
ORD IDord-4657552f46714ae0bf3713832eda6a1f
Source noteuspto-grants-1976_04