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HRID1606355

反应详情

EQUATION

反应方程式

HRID 1606355 的结构方程式

REACTANTS

反应物

2
结构：C1COCCN1
HCID8083

Morpholine

C4H9NO

结构：CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](OCCCl)C[C@]4(C)[C@H]3C(=O)C[C@]12C
HCID22789153

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](OCCN5CCOCC5)C[C@]4(C)[C@H]3C(=O)C[C@]12C
HCID22789169

未命名化合物

PROCEDURE

实验过程

2β(2'-Chloroethoxy)-3α-hydroxy-5α-pregnane-11,20-dione (100 mg.) was dissolved in morpholine (10 ml.) and the solution heated on a steam-bath for 24 hours, complete reaction occurring. The morpholine was evaporated off in vacuo and the orange oil obtained purified by preparative TLC in ethyl acetate to give the title compound (40 mg.) as a pale yellow oil.

WORKUP

后处理

  1. temperaturethe solution heated on a steam-bath for 24 hours
  2. customcomplete reaction
  3. customThe morpholine was evaporated off in vacuo
  4. customthe orange oil obtained
  5. custompurified by preparative TLC in ethyl acetate