Morpholine → HCID 22789169, compound

Participants

Reaction Steps

2β(2'-Chloroethoxy)-3α-hydroxy-5α-pregnane-11,20-dione (100 mg.) was dissolved in morpholine (10 ml.) and the solution heated on a steam-bath for 24 hours, complete reaction occurring. The morpholine was evaporated off in vacuo and the orange oil obtained purified by preparative TLC in ethyl acetate to give the title compound (40 mg.) as a pale yellow oil.

Provenance & Evidence