N-(4-Hydroxyphenyl)glycine → L-Tyrosine

HRID 1606460Notes

Reaction equation

HRID 1606460 reaction equation
[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1N=CN[CH:5]=1.[OH:12][C:13]1[CH:18]=CC(NCC(O)=O)=[CH:15][CH:14]=1>>[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[CH:15]=[CH:14][C:13]([OH:12])=[CH:18][CH:5]=1

Participants

3

Reactant 2

HCID 67149N-(4-Hydroxyphenyl)glycineHCID 178419078HCID 178419078, compound

Product 1

HCID 6057L-Tyrosine

Procedure

The above procedure is repeated using the methyl and ethyl esters of histidine and 4-hydroxy phenylglycine, and the ethyl ester of L-tyrosine to produce the corresponding amino acid ester derivatives.

Sources & evidence

ORD record
ord-b20eb97fa1c6466d928712babdb655bd
Source dataset
uspto-grants-1976_04
Patent number
US03953431

Reaction notes

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