HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 138413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-phenyl-2-pyridin-3-ylethanol | HCID 238338 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 138413 | HCID 138413 | 71.5% |
Reaction Steps
A mixture of crude 2-(3-pyridyl)-1-phenylethanol (20 g), glacial acetic acid (200 ml) and concentrated HCl (50 ml) is refluxed for 16 hours, then evaporated to dryness in vacuo. The oily hydrochloride is taken up in water, extracted with ether and methylene chloride, and then liberated with bicarbonate. Extraction (CH2Cl2) and drying (K2CO3) affords 13 g of β-(3-pyridyl)styrene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03953434 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-dcdf81f575f14605b562cd3fe9157e7a |
| Source note | uspto-grants-1976_04 |