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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1606506Generated: November 1, 2026

Anisole → HCID 21543499, compound

https://huagongshe.com/reaction/1606506

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnisoleHCID 7519—
Reactant4-FluoroiodobenzeneHCID 9605—
ReactantSodium CarbonateHCID 10340—
ReactantHCID 21543497HCID 21543497—
CatalystCopperHCID 23978—
ProductHCID 21543499HCID 21543499—

Reaction Steps

A mixture of 15g (0.067 mole) of 5-chloro-3-[2-(1,3-dioxolan-2-yl)propyl] indole, 225 ml of anisole, 30g (0.135 mole) of 4-fluoroiodobenzene, 30g of copper powder and 60g of dry sodium carbonate are heated to reflux for 96 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03953442
Source datasetuspto-grants-1976_04
ORD IDord-606efb4bfb00465a93789e308a8bdb93
Source noteuspto-grants-1976_04