反应详情

2-Hydrazinoquinoline (15.9 grams; 0.1 mole) was placed in a 250-milliliter three-necked flask equipped with a condenser, along with 70 milliliters of diphenyl ether. To the flask was then added 11.9 grams (0.1 mole) of phenyl isocyanate. The reaction mixture was allowed to reflux for three hours, cooled, and allowed to stand at room temperature overnight. In the morning the precipitate, the desired s-triazolo(4,3-a)quinolin-1-ol product, was filtered off and recrystallized from water. The product so obtained melted at 133.5°-4.5°C.

1. temperatureto reflux for three hours
2. temperaturecooled
3. filtrationIn the morning the precipitate, the desired s-triazolo(4,3-a)quinolin-1-ol product, was filtered off
4. customrecrystallized from water