Methanol → Methyl 6-(3-chloro-4-fluorobenzyl)-4-methoxy-2-[4-(methylamino)butyl]-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxylate
Reaction equation
[CH3:33][Si:34]([CH:35]=[N+:36]=[N-:37])([CH3:38])[CH3:39].[CH3:40][CH2:41][CH2:42][CH2:43][CH2:44][CH3:45].[CH3:46][OH:47].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:28])[c:8]3[c:9]([OH:27])[c:10](=[O:26])[n:11]([CH2:20][CH2:21][CH2:22][CH2:23][NH:24][CH3:25])[c:12]([C:16](=[O:17])[O:18][CH3:19])[c:13]3[CH2:14][CH2:15]2)[cH:29][cH:30][c:31]1[F:32].[Cl:48][CH2:49][Cl:50]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:28])[c:8]3[c:9]([O:27][CH3:33])[c:10](=[O:26])[n:11]([CH2:20][CH2:21][CH2:22][CH2:23][NH:24][CH3:25])[c:12]([C:16](=[O:17])[O:18][CH3:19])[c:13]3[CH2:14][CH2:15]2)[cH:29][cH:30][c:31]1[F:32]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5f2ab72ab0864cda96bd31ecf864b3a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…