Methylamine → HCID 70542314, compound

HRID 1606550Notes

Reaction equation

HRID 1606550 reaction equation
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:10]=[CH:9][O:8][N:7]=1.[N+](C=C(SC)SC)([O-])=O.[N+:20]([CH:23]=[C:24](SC)[NH:25][CH2:26]CSCC1C=CON=1)([O-:22])=[O:21].CN>>[N+:20]([CH:23]=[C:24]([NH:25][CH3:26])[NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:10]=[CH:9][O:8][N:7]=1)([O-:22])=[O:21]

Participants

5

Reactant 4

HCID 6329MethylamineHCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 129234172-((Isoxazol-3-ylmethyl)thio)ethanamineHCID 705444111-Nitro-2-methylthio-2-[2-(3-isoxazolylmethylthio)ethylamino]ethylene

Product 1

HCID 70542314HCID 70542314, compound

Procedure

Reaction of 3-[(2-aminoethyl)thiomethyl]isoxazole (from the dihydrobromide (3.8 g)) with 1-nitro-2,2-bis-methylthioethylene (2.0 g) by the procedure of Example 4(i) and treatment of the resultant 1-nitro-2-methylthio-2-[2-(3-isoxazolylmethylthio)ethylamino]ethylene with methylamine according to the procedure of Example 3(ii) gives 1-nitro-2-methylamino-2-[2-(3-isoxazolylmethylthio)ethylamino]ethylene.

Sources & evidence

ORD record
ord-69445a46414b413787f6e908627d312c
Source dataset
uspto-grants-1976_04
Patent number
US03953460

Reaction notes

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