Water → HCID 178474504, compound

HRID 1606552Notes

Reaction equation

HRID 1606552 reaction equation
[NH:1]=[C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[SH:4](=[O:17])([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[NH:3]1.[C:18](Cl)(=[O:20])[CH3:19].C(N(CC)CC)C.O>O1CCOCC1>[C:18]([N:1]=[C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[SH:4](=[O:17])([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[NH:3]1)(=[O:20])[CH3:19]

Participants

6

Reactant 4

HCID 962WaterHCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 178509313HCID 178509313, compound

Product 1

HCID 178474504HCID 178474504, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1.2 g. 3-imino-1-phenyl-3H-1,2-benzisothiazole-1-oxide are heated under reflux for 15 minutes with 0.4 g. acetyl chloride and 0.7 g. triethylamine in dioxan. Thereafter, the reaction mixture is poured into water and the precipitate obtained is filtered off with suction and recrystallised from ethyl acetate. There is thus obtained 3-(acetylimino)-1-phenyl-3H-1,2-benzisothiazole-1-oxide; m.p . 119°C.

Workup

  1. temperatureunder reflux for 15 minutes with 0.4 g
  2. customthe precipitate obtained
  3. filtrationis filtered off with suction
  4. customrecrystallised from ethyl acetate
  5. custom119°C.

Sources & evidence

ORD record
ord-35a941d0496648eaae55a62d1babeb2c
Source dataset
uspto-grants-1976_04
Patent number
US03953464

Reaction notes

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