Triethylamine → HCID 178521409, compound

HRID 1606555Notes

Reaction equation

HRID 1606555 reaction equation
[NH:1]=[C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[SH:4](=[O:17])([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[NH:3]1.C(N(CC)CC)C.[Cl:25][C:26]1[CH:36]=[CH:35][C:29]([O:30][CH2:31][C:32](Cl)=[O:33])=[CH:28][CH:27]=1>C(Cl)(Cl)Cl>[Cl:25][C:26]1[CH:36]=[CH:35][C:29]([O:30][CH2:31][C:32]([N:1]=[C:2]2[C:6]3[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=3[SH:4](=[O:17])([C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:3]2)=[O:33])=[CH:28][CH:27]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 77771p-Chlorophenoxyacetyl chlorideHCID 178509313HCID 178509313, compound

Product 1

HCID 178521409HCID 178521409, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

24 g. 3-imino-1-phenyl-3H-1,2-benzisothiazole-1-oxide, 13.2 g. triethylamine and 21 g. 4-chlorophenoxyacetyl chloride are heated under reflux for 1 hour in 1 liter chloroform. After working up the reaction mixture in the usual manner, there is obtained 3-(4-chlorophenoxyacetylimino)-1-phenyl-3H-1,2-benzisothiazole-1-oxide which, after recrystallisation from acetonitrile, is obtained in the form of colourless, felted needles melting at 196°C.

Sources & evidence

ORD record
ord-24e47cbcbe10492ab08fddddaf875ffb
Source dataset
uspto-grants-1976_04
Patent number
US03953464

Reaction notes

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