29476-22-0 → HCID 21543836, compound

HRID 1606576Notes

Reaction equation

HRID 1606576 reaction equation
[C:1]1(C2CC(=O)NC3C=CC=CC=3S2)C=CC=C[CH:2]=1.[ClH:19].[CH3:20][N:21]([CH3:45])[CH2:22][CH2:23][N:24]([CH3:44])[C:25]([N:27]1[C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][C:32]=2S[CH:30]([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)[CH2:29][CH2:28]1)=[O:26]>>[ClH:19].[CH3:20][N:21]([CH3:45])[CH2:22][CH2:23][N:24]([CH3:44])[C:25]([N:27]1[C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][C:32]=2[CH2:2][CH2:1][CH:30]([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)[CH2:29][CH2:28]1)=[O:26]

Participants

3

Reactant 2

HCID 38949029476-22-0HCID 131710162HCID 131710162, compound

Product 1

HCID 21543836HCID 21543836, compound

Procedure

By substituting an equivalent amount of 3,4,5,6-tetrahydro-4-phenyl-1-benzazocin-2(H)-one, m.p. 188°-189° (prepared as described in Example 1 of U.S. patent application, Ser. No. 418,910, filed Dec. 16, 1964), for the 2,3-dihydro-2-phenyl-1,5-benzothiazepin-4-one in part (A) of Example 1 and carrying out the precedure of the Example, there is obtained N-(2-dimethylaminoethyl)-1,2,3,4,5,6-hexahydro-N-methyl-4-phenyl-benzazocine-1carboxamide hydrochloride.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-ebea9e87803b47f29bcaa0593cba0780
Source dataset
uspto-grants-1976_04
Patent number
US03953469

Reaction notes

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