Acetyl chloride → HCID 21427279, compound

HRID 1606670Notes

Reaction equation

HRID 1606670 reaction equation
[CH3:1][NH:2][C:3](=[O:28])[C@H:4](CC1C=CC=CC=1)[NH:5][C:6](=[O:20])[C:7]1[C:12]([I:13])=[C:11]([NH2:14])[C:10]([I:15])=[C:9]([C:16]([OH:18])=[O:17])[C:8]=1[I:19].[C:29](Cl)(=[O:31])[CH3:30].[CH3:33]C(N(C)C)=O>>[CH3:33][N:2]([CH3:1])[C:3](=[O:28])[CH2:4][NH:5][C:6](=[O:20])[C:7]1[C:12]([I:13])=[C:11]([NH:14][C:29](=[O:31])[CH3:30])[C:10]([I:15])=[C:9]([C:16]([OH:18])=[O:17])[C:8]=1[I:19]

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 31374DimethylacetamideHCID 54110808HCID 54110808, compound

Product 1

HCID 21427279HCID 21427279, compound

Procedure

Analogously to Example 1, N-(3-carboxy-5-amino-2,4,6-triiodobenzoyl)-glycine dimethylamide (IV n), m.p. 239°-241° C. (under decomposition) is acetylated with acetyl chloride in dimethylacetamide.

Sources & evidence

ORD record
ord-652985e1b0ce4be1b4a3a72a338fa369
Source dataset
uspto-grants-1976_04
Patent number
US03953501

Reaction notes

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