Methyl iodide → HCID 21544473, compound

HRID 1606760Notes

Reaction equation

HRID 1606760 reaction equation
[SH:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([Cl:11])[CH:10]=1)[C:5]([OH:7])=[O:6].[CH3:12]I.[OH-].[K+]>CO>[CH3:12][S:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([Cl:11])[CH:10]=1)[C:5]([OH:7])=[O:6]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 14797Potassium HydroxideHCID 215423303-Chloro-5-mercaptobenzoic acid

Product 1

HCID 21544473HCID 21544473, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a manner similar to procedure of Example 14, 3-mercapto-5-chlorobenzoic acid is contacted with methyl iodide in methanol containing potassium hydroxide as the base to yield the desired product in 70% yield, m.p. 148°-150° C.

Sources & evidence

ORD record
ord-386271569b4e45ca9dd785fe67619564
Source dataset
uspto-grants-1976_04
Patent number
US03953595

Reaction notes

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