HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 21544460, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-Chloroacetophenone | HCID 10757 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-Chloro-2-sulfanylbenzoic acid | HCID 15557787 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21544460 | HCID 21544460 | — |
Reaction Steps
A solution of 18.9 g. (0.1 mole) of 5-chlorothiosalicylic acid, 15.4 g. (0.1 mole) of α-chloroacetophenone and 8 g. (0.2 mole) of sodium hydroxide in 200 ml. of ethanol containing 45 ml. of water is heated to reflux for 2 hours. After removing one-fourth the alcohol under reduced pressure, the mixture is acidified with hydrochloric acid and the resulting precipitated product filtered, 5.0 g., m.p. 154°-156° C. The analytical sample has a melting point of 156°-157.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03953595 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-c658e2c1876446b9aa0e67da87a080a2 |
| Source note | uspto-grants-1976_04 |