反应详情

温度

50 °C

A mixture of sodium thiomethoxide (317 mg) and 5-bromo-2-fluorobenzotrifluoride (1.0 g) in DMF (4 ml) was heated at 50° C. for 1 h then poured into water and extracted with isohexane. The organics were washed with brine, dried and concentrated in vacuo to give the sub-title compound (762 mg).

1. extractionextracted with isohexane
2. washThe organics were washed with brine
3. customdried
4. concentrationconcentrated in vacuo