Benzyltrimethylammonium hydroxide → HCID 54073604, compound

Participants

Reaction Steps

A solution of 2,6-dihydroxyacetophenone (15.2 g), p-cyanophenylglycidyl ether (17.5 g) and benzyltrimethylammonium hydroxide (10 drops of a 40% solution) was heated under reflux for 2 days. The solvent was then removed by evaporation under reduced pressure to give 1-(2-acetyl-3-hydroxyphenoxy)-2-hydroxy-3-p-cyanophenoxypropane, 28.4 g, as a beige solid. A portion was recrystallized from ethanol affording cream prisms m.p. 157°-158°.

Provenance & Evidence