Hydrochloric Acid → 2-(beta-Hydroxyethyl)amino-4-(beta-hydroxyethyl)amino-6-(beta-hydroxyethyl)aminonitrobenzene

Participants

Reaction Steps

0.0072 mole (2 g) of 2-(β-hydroxyethyl)amino-6-(β-hydroxyethyl)amino-4-chloronitrobenzene, synthesized in stage 1 of example 2, was heated at 100°-110° C. with 6 ml of ethanolamine for 6 hours. The reaction medium was diluted with ice water then brought to neutrallity by addition of concentrated hydrochloric acid to precipitate out the desired product. After filtering and hot drying under vacuum in the presence of P2O5, it was recrystallized from 96° ethanol. It melted at 200° C.

Provenance & Evidence