1,1'-Carbonyldiimidazole → HCID 19851510, compound

HRID 1606925Notes

Reaction equation

HRID 1606925 reaction equation
[CH3:1][O:2][C:3]1[C:8]([C:9]([OH:11])=O)=[CH:7][N:6]=[C:5]([NH:12][CH3:13])[N:4]=1.C(N1C=CN=C1)(N1C=CN=C1)=O.[NH2:26][CH:27]1[CH:32]2[CH2:33][CH2:34][N:29]([CH2:30][CH2:31]2)[CH2:28]1>>[N:29]12[CH2:34][CH2:33][CH:32]([CH2:31][CH2:30]1)[CH:27]([NH:26][C:9]([C:8]1[C:3]([O:2][CH3:1])=[N:4][C:5]([NH:12][CH3:13])=[N:6][CH:7]=1)=[O:11])[CH2:28]2

Participants

4

Reactant 3

HCID 682631,1'-CarbonyldiimidazoleHCID 1232383-AminoquinuclidineHCID 129017024-Methoxy-2-(methylamino)pyrimidine-5-carboxylic acid

Product 1

HCID 19851510HCID 19851510, compound

Procedure

Following the procedure of Example 22, 4-methoxy-2-(methylamino)-5-pyrimidinecarboxylic acid, 1,1'-carbonyl-diimidazole and 3-aminoquinuclidine are reacted to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-030b8bfe85dd40a195248a737774d206
Source dataset
uspto-grants-1989_09
Patent number
US04863919

Reaction notes

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