Chlorosuccinimide → HCID 14456311, compound

HRID 1607070Notes

Reaction equation

ClN1[C:6](=[O:7])[CH2:5]CC1=O.Br[C:10]1[C:24]2=[C:25]3[C:13]([N:14]([Si](C(C)(C)C)(C)C)[CH:15]=[C:16]3[CH2:17][C@@H:18]3[C@@H:23]2[CH2:22][C@H:21]([NH:26][C:27](=[O:33])[N:28]([CH2:31][CH3:32])[CH2:29][CH3:30])[CH2:20][N:19]3[CH3:34])=[CH:12][CH:11]=1>>[C:6]([C:11]1[CH:12]=[C:13]2[C:25]3[C:16]([CH2:17][C@@H:18]4[C@@H:23]([C:24]=3[CH:10]=1)[CH2:22][C@H:21]([NH:26][C:27](=[O:33])[N:28]([CH2:29][CH3:30])[CH2:31][CH3:32])[CH2:20][N:19]4[CH3:34])=[CH:15][NH:14]2)(=[O:7])[CH3:5]

Participants

Reactant 2

HCID 31398Chlorosuccinimide

HCID 13823174HCID 13823174, compound

Product 1

HCID 14456311HCID 14456311, compound

Procedure

With N-chlorosuccinimide and 3-(12-bromo-1-tert-butyldimethylsilyl-6-methyl-8α-ergolinyl)-1,1-diethylurea:

Sources & evidence

ORD record: ord-f52256018f60493eb2c89565d201f284
Source dataset: uspto-grants-1989_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04863929

Reaction notes

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