Triethylamine → HCID 54016037, compound

Participants

Reaction Steps

N-triphenylmethyl-2-methylaminothiocarbonylthioethylamine (0.89 g) which was prepared by the method of Reference 5 was subjected to a similar reaction to that described in Reference 4 to prepare 2-methylaminothiocarbonylthioethylamine (crude formate: 223 mg). The product was dissolved in anhydrous methanol (7 L ml). Triethylamine (732 μl) and mitomycin A (316 mg: 0.8 molar equivalent) were added to the reaction solution which was then treated in a similar manner to that described in Example 1 to obtain Compound 25 (233 mg) in the form of grayish blue powders with a yield of 44%.

Provenance & Evidence