Formamide → HCID 178473798, compound

Participants

Reaction Steps

A mixture of 3.0 g. (0.01 mole) 1-acetyl-5,6-diamino-3,3-dimethylindoline dihydrochloride (Example 2b) and 35 ml. formamide is heated to reflx for 40 minutes and then evaporated. The residue is mixed with water, extracted with dichloromethane and the extract evaporated to give 2.6 g. (85% of theory) of the title compound; m.p. 214°-216° C.

Provenance & Evidence