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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1607193Generated: October 31, 2026

Phosphinic Acid → HCID 14621046, compound

https://huagongshe.com/reaction/1607193

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphinic AcidHCID 4124402—
ReactantHCID 14621043HCID 14621043—
ProductHCID 14621046HCID 14621046—

Reaction Steps

By using the procedure of Example 18, 4-amino-α-[(tert-butylamino)methyl]-2,3-difluorobenzyl alcohol is deaminated with H3PO2 to afford the title compound. Similarly, 2,3-difluoro-α-[(isopropylamino)methyl]benzyl alcohol is obtained from its corresponding 4-amino compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04863959
Source datasetuspto-grants-1989_09
ORD IDord-4069c74db9e0469589127cd3168bfdbd
Source noteuspto-grants-1989_09