Triethylamine → HCID 14621106, compound

HRID 1607201Notes

Reaction equation

HRID 1607201 reaction equation
[C:1]([C:4]1[C:5]([F:13])=[C:6]([CH:9]=[C:10](Cl)[CH:11]=1)[C:7]#[N:8])(=[O:3])[CH3:2].C(N(CC)CC)C>CO.[H][H].[Pd]>[C:1]([C:4]1[C:5]([F:13])=[C:6]([CH:9]=[CH:10][CH:11]=1)[C:7]#[N:8])(=[O:3])[CH3:2]

Participants

5

Reactant 2

HCID 8471TriethylamineHCID 14621099HCID 14621099, compound

Product 1

HCID 14621106HCID 14621106, compound

Reagents, catalysts & solvents 2

HCID 178506449HCID 178506449, compoundCatalystHCID 887MethanolSolvent

Procedure

Reduction of 3-acetyl-5-chloro-2-fluorobenzonitrile in methanol using H2 /Pd-C for 3 h under 45 p.s.i.g. of H2 in the presence of triethylamine affords 3-acetyl-2-fluorobenzonitrile, which is the starting material.

Workup

  1. customfor 3 h

Sources & evidence

ORD record
ord-f8988d77ee5f41c5a07e7b243ea1adfa
Source dataset
uspto-grants-1989_09
Patent number
US04863959

Reaction notes

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