HCID 14579773, compound → HCID 14579774, compound

HRID 1607281Notes

Reaction equation

HRID 1607281 reaction equation
[CH3:1][O:2][C:3]1[CH:24]=[CH:23][C:6]([CH2:7][CH2:8][C:9]2[O:10][C:11]3[CH:18]=[CH:17][C:16]([CH2:19][CH:20]=[CH2:21])=[C:15]([OH:22])[C:12]=3[C:13]=2[CH3:14])=[CH:5][CH:4]=1>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH2:8][C:9]2[O:10][C:11]3[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][CH3:21])=[C:15]([OH:22])[C:12]=3[C:13]=2[CH3:14])=[CH:23][CH:24]=1

Participants

4

Reactant 1

HCID 14579773HCID 14579773, compound

Product 1

HCID 14579774HCID 14579774, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 2-(p-methoxyphenethyl)-3-methyl-4-hydroxy-5-allylbenzofuran (0.65 gm, 2 mmoles) in ethanol (50 mL) was hydrogenated in a Parr hydrogenator in the presence of 5% palladium on charcoal at 50 psi for a period of 2 hours. The catalyst was filtered off and the filtrate was concentrated in vacuo to yield 2-(p-methoxyphenethyl)-3-methyl-4-hydroxy-5-propylbenzofuran, mp 77°-79° C.

Workup

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-56da9e83620f4e0b8b95668cc85ad49a
Source dataset
uspto-grants-1989_09
Patent number
US04863958

Reaction notes

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