Hydrochloric Acid → HCID 13186853, compound

Participants

Reaction Steps

39.5 g of 2-nitropropane and 27 g of 4-(2-methoxyethyl)-phenoxy-acetaldehyde are successively added dropwise to a solution of 2 g of sodium in 150 ml of methanol. After the mixture has been stirred at room temperature for 15 hours, the solution is poured onto water and acidified with 2N HCl. Extraction with CHCl3 gives, after crystallisation from diisopropyl ether, 23.3 g of the nitro compound mentioned in the title. Melting point: 92°-94° C.

Provenance & Evidence