2-(6-Methoxy-2-naphthyl)propionic acid → 2-(6-Methoxynaphthalen-2-yl)propanoic acid--ethanamine (1/1)

Participants

Reaction Conditions

Reaction Steps

230 g (1 mole) of (±)-2-(6-methoxy-2-naphthyl) propionic acid was dissolved in 1.5 l of acetone at about 45° C. By addition of 64 g (1 mole) of a 70% w/w aqueous monoethylamine solution, the ethylamine salt crystallized. The mixture was cooled to about 25° C., filtered and washed portionwise with 200 ml of acetone.

Provenance & Evidence