Hydrochloric Acid → 2-(6-Methoxy-2-naphthyl)propionic acid

HRID 1607489Notes

Reaction equation

HRID 1607489 reaction equation
C(N)C.[CH3:4][O:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[CH:12]=[C:11]([CH:16]([CH3:20])[C:17]([OH:19])=[O:18])[CH:10]=[CH:9]2.Cl>O>[CH3:4][O:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[CH:12]=[C:11]([CH:16]([CH3:20])[C:17]([OH:19])=[O:18])[CH:10]=[CH:9]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 441538962-(6-Methoxynaphthalen-2-yl)propanoic acid--ethanamine (1/1)

Product 1

HCID 13022-(6-Methoxy-2-naphthyl)propionic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

220 g of (+)-2-(6-methoxy-2-naphthyl) propionic acid ethylamine salt was dissolved in 1350 ml of water at 70° C. The obtained completely clear solution was slowly acidified to about pH=5 with 10% w/w hydrochloric acid.

Workup

  1. customThe obtained completely clear solution

Sources & evidence

ORD record
ord-49fca592bea84394b8d539ebfed97057
Source dataset
uspto-grants-1989_09
Patent number
US04865770

Reaction notes

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