HuagongsheHuagongshe Chemistry Print Report · For research reference only
N'-Hydroxycyclopropanecarboximidamide → 4,5-Dihydro-5-methyl-6-(3-methyl-1,2,4-oxadiazol-5-yl)-4-oxo-imidazo[1,5-a]thieno[3,2-e]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N'-Hydroxycyclopropanecarboximidamide | HCID 2794666 | — |
| Reactant | Ethyl 4,5-dihydro-5-methyl-4-oxo-imidazo[1,5-a]thieno[3,2-e]pyrimidine-6-carboxylate | HCID 15085581 | — |
| Reactant | 6-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4,5-dihydro-5-methyl-4-oxo-imidazo[1,5-a]thieno[3,2-e]pyrimidine | HCID 15085590 | — |
| Product | 4,5-Dihydro-5-methyl-6-(3-methyl-1,2,4-oxadiazol-5-yl)-4-oxo-imidazo[1,5-a]thieno[3,2-e]pyrimidine | HCID 15085589 | — |
Reaction Steps
In the same manner 6-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-4,5-dihydro-5-methyl-4-oxo-imidazo[1,5-a]thieno[3,2-e]pyrimidine, m.p. 218°-219° C., was prepared from ethyl 4,5-dihydro-5-methyl- 4-oxo-imidazo[1,5-a]thieno[3,2-e]pyrimidine-6-carboxylate and cyclopropan carboxamide oxime (Compound 18).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04866065 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-54f3dfe9b6914d6fb52f2cbde01bc005 |
| Source note | uspto-grants-1989_09 |