Iodoethane → HCID 14184042, compound

Participants

Reaction Steps

In 100 ml of methyl-ethyl-ketone 4.45 g (20 millimoles) of 6-hydroxy-7-methoxy-2,2-dimethyl-4-chromanone are dissolved, whereupon 4.1 g (30 millimoles) of potassium carbonate and 4.7 g (2.4 ml, 30 millimoles) of ethyl iodide are added and the reaction mixture is refluxed for 5 hours. The precipitated inorganic salt is filtered off, washed twice with 20 ml of acetone each and the solvent is removed. The residue is crystallized from 90% ethanol. Thus 4.75 g of the desired compound are obtained, yield 95%. Mp.: 86°-87° C.

Provenance & Evidence