Phosphorus pentachloride → HCID 10448313, compound

HRID 1607663Notes

Reaction equation

HRID 1607663 reaction equation
[F:1][C:2]1[CH:20]=[C:19]([F:21])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][C:13]=1[N+:14]([O-:16])=[O:15])[C:8](O)=[O:9].P(Cl)(Cl)(Cl)(Cl)[Cl:23]>C1C=CC=CC=1>[F:1][C:2]1[CH:20]=[C:19]([F:21])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][C:13]=1[N+:14]([O-:16])=[O:15])[C:8]([Cl:23])=[O:9]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 10402218HCID 10402218, compound

Product 1

HCID 10448313HCID 10448313, compoundYield 103.5%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 3-(2,4-difluorophenoxy)-4-nitrobenzoic acid (1 g) and phosphorus pentachloride (0.74 g) in benzene (10 ml) was stirred for 30 minutes at room temperature. Benzene was evaporated under reduced pressure to give an oil of 3-(2,4-difluorophenoxy)-4-nitrobenzoyl chloride (1.1 g).

Workup

  1. customBenzene was evaporated under reduced pressure

Sources & evidence

ORD record
ord-640483cf46be44968e71f30b77f34dec
Source dataset
uspto-grants-1989_09
Patent number
US04866091

Reaction notes

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