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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1607868Generated: November 1, 2026

L-Pyroglutamic Acid → N-[Hydroxy(5-hydroxy-3,4-dihydro-2H-pyrrol-2-yl)methylidene]glycine

https://huagongshe.com/reaction/1607868

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Pyroglutamic AcidHCID 7405—
ReactantN-(tert-butoxycarbonyl)glycineHCID 78288—
ProductN-[Hydroxy(5-hydroxy-3,4-dihydro-2H-pyrrol-2-yl)methylidene]glycineHCID 152981—

Reaction Steps

2 mmoles of Boc-Gly-Rx were used as starting material, and 0.90 g of pGlu were added according to the usual principles for solid peptide synthesis.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04868156
Source datasetuspto-grants-1989_09
ORD IDord-f9fdfceba0f24412be332e3a9f318530
Source noteuspto-grants-1989_09