HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 19849744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Bromodiphenylmethane | HCID 236603 | — |
| Reactant | HCID 19849736 | HCID 19849736 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 19849744 | HCID 19849744 | — |
Reaction Steps
A solution containing 10.4 g of 1-[3-[bis(4-fluorophenyl)methoxy]propyl]piperazine, 4.6 ml of triethylamine and 8.1 g of benzhydryl bromide in 100 ml of anhydrous xylene is refluxed for 8 hours and then cooled down. The mixture is washedwith water, dried over anhydrous magnesium sulfate and evaporated under reduced pressure. The resiude is recrystallized from n-hexane to give the aimed product, m.p.: 78°-79° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04868184 |
| Source dataset | uspto-grants-1989_09 |
| ORD ID | ord-98b0bc7707b448c195f08e3f35c62f94 |
| Source note | uspto-grants-1989_09 |