Boron tribromide → 85893-94-3

Participants

Reaction Steps

A mixture containing 8.2 g of 3-(2,3-dichloro-4-methoxyphenyl)benzisothiazole, 100 ml of 1,2-dichloroethane and 100 ml of BBr3 was refluxed for 30 minutes. Itwas then poured into ice/water and the organic solvent was removed under reduced pressure. The product was then filtered off, washed with hexane and dried to give 7.50 g (96%) of 4-(benzisothiazol-3-yl)-2,3-dichlorophenol.

Provenance & Evidence