Phenol → 4'-Hydroxyacetophenone
Reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:8](OC(=O)C)(=[O:10])[CH3:9]>>[CH3:9][C:8]([C:4]1[CH:3]=[CH:2][C:1]([OH:7])=[CH:6][CH:5]=1)=[O:10]Participants
3
Reactant 2
Product 1
Procedure
acylating phenol, preferably with acetic anhydride and using HF as a catalyst to produce 4-hydroxyacetophenone; and
Sources & evidence
- ORD record
- ord-d98e05c2225b4106b739ad9e41eed79e
- Source dataset
- uspto-grants-1989_09
- Patent number
- US04868256
Reaction notes
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