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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1607962Generated: October 30, 2026

Phenol → 4'-Hydroxyacetophenone

https://huagongshe.com/reaction/1607962

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
ReactantAcetic AnhydrideHCID 7918—
Product4'-HydroxyacetophenoneHCID 7469—

Reaction Steps

acylating phenol, preferably with acetic anhydride and using HF as a catalyst to produce 4-hydroxyacetophenone; and

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04868256
Source datasetuspto-grants-1989_09
ORD IDord-d98e05c2225b4106b739ad9e41eed79e
Source noteuspto-grants-1989_09