Hydrochloric Acid → HCID 178505829, compound

HRID 1608038Notes

Reaction equation

HRID 1608038 reaction equation
C([NH+](CC)CC)C.[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([NH:15][C:16](=S)[SH:17])=[C:11]([F:19])[CH:10]=1.[OH-].[Na+].[N-:22]=[N+:23]=[N-:24].[Na+].Cl>O>[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[C:16](=[S:17])[NH:24][N:23]=[N:22]2)=[C:11]([F:19])[CH:10]=1

Participants

7

Reactant 5

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 33557Sodium AzideHCID 1385867TriethylammoniumHCID 198503494-Chloro-2-fluorophenyl dithiocarbamic acid

Product 1

HCID 178505829HCID 178505829, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A stirred mixture of 5.0 g (0.016 mole) of the triethylammonium salt of 4-chloro-2-fluorophenyl dithiocarbamic acid, 0.62 g (0.016 mole) of sodium hydroxide, and 4.0 g (0.062 mole) of sodium azide in 10 ml of water was heated at reflux for three hours. The mixture was cooled to room temperature and was acidified with concentrated hydrochloric acid. A precipitate formed and was collected by filtration. The filter cake was washed with water and was dried to yield 3.2 g of 1-(4-chloro-2-fluorophenyl)-1,4-dihydro-5H-tetrazol-5-thione, m.p. 128° C.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for three hours
  3. customA precipitate formed
  4. filtrationwas collected by filtration
  5. washThe filter cake was washed with water
  6. customwas dried

Sources & evidence

ORD record
ord-a30c149b61ef47c39d36ce6adcca70e0
Source dataset
uspto-grants-1989_09
Patent number
US04868321

Reaction notes

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